BaO·6Fe2O3 as DDS using tetracycline as model drug

This paper focuses on the loading and release studies of tetracycline as model drug from spherical aggregates of micron size (approx. 1.2 μm in diameter) of barium hexaferrite (BaO·6Fe2O3) synthetized from wet chemical sol-gel method via spray drying. BaO·6Fe2O3 aggregates were characterized using x-ray diffraction and scanning electron microscopy. The load capacity of BaO·6Fe2O3 systems was reached at 40 minutes after contact with tetracycline drug. Release of tetracycline was confirm from E. coli bacterial death when BaO·6Fe2O3 particles were in contact with the bacteria.